Atenolol For High Blood Pressure, Chest Pain and Survival After Heart Attacks Overview
Atenolol is a prescription medication used to treat high blood pressure, to prevent chest pain, and to improve survival after a heart attack in adults. Atenolol belongs to a class of drugs called beta blockers, which relax blood vessels and slows the heart rate down. This medication comes in tablet form and is taken once or twice a day, with or without food. This medication is also available in injectable form to be given directly into a vein by a healthcare professional. Common side effects of atenolol include tiredness, nausea, and dizziness. Do not drive or operate heavy machinery until you know how atenolol.
Overview of Metoprolol Used to Treat High Blood Pressure
Metoprolol is a prescription medication used to treat high blood pressure, chest pain, heart failure, and is also used to improve survival after a heart attack. Metoprolol belongs to a group of drugs called betablockers, which work by relaxing blood vessels and slowing your heart rate in order to improve blood flow and to decrease blood pressure. This medication comes in an immediate release tablet form and an injectable form. The tablet is taken once or twice daily, and the injectable form is administered by your healthcare provider. Metoprolol also comes as an extended release tablet form, which is taken once a day.
Coreg CR For the Treatment of Heart Failure and High Blood Pressure in Adults Overview
Coreg CR, the brandname form of carvedilol, is a prescription medication used to treat symptoms of heart failure and high blood pressure in adults. Coreg CR belongs to a group of drugs called beta blockers. These work by relaxing blood vessels and decreasing the heart rate to improve blood flow and reduce blood pressure. This medication comes in capsule form and is usually taken once a day with food. Common side effects of Coreg CR include a slower heart rate, fatigue, and shortness of breath. Coreg CR can also cause dizziness. Do not drive or operate heavy machinery until you.
When Less Is More Low Dose Beta Blockers
A new study from Northwestern University found that the dose of betablockers prescribed to heart attack patients can likely be significantly reduced without sacrificing effectiveness. In fact, patients on low doses may live just as long or even longer than patients on higher doses. The lead doctor launched this study when he noticed that many patients were being treated with lower doses of betablockers than those typically used in clinical trials. He was initially concerned that patients were receiving poor care, but the results of this study shocked him and proved otherwise since patients on lower doses of beta blockers survived.
EXPERT TIME FOR A BETABLOCKER UPGRADE
GtgtNarrator AFTER BEING DIAGNOSED WITH AN IRREGULAR HEARTBEAT, MARK BERO pronounced BEEroh KNEW HE HAD TO MAKE CHANGES. SOME LIKE WALKING MORE AND EATING HEALTHIER ARE PERMANENT CHANGES. BUT OTHERS, LIKE HIS DAILY DOSE OF BETA BLOCKERS, ARE TEMPORARY. gtgtMark Bero The doctor is projecting that within the next 18 months at the most to where I can be weaned away from the medications that I'm currently on. gtgtNarrator THE BETA BLOCKERS HELP CONTROL MARK'S HEART AND OVER THE LAST 60 YEARS HAVE BEEN EXTREMELY POPULAR. IN FACT, BETA BLOCKERS ARE PRESCRIBED FOR.
EVERYTHING FROM HEART FAILURE TO HIGH BLOOD PRESSURE. FROM TREATING GLAUCOMA TO PREVENTING MIGRAINES. AND IN THE LAST DECADE, SALES OF BETA BLOCKERS HAVE SHOT UP MORE THAN 20PERCENT. BUT MILLIONS OF THOSE PRESCRIPTIONS ARE CAUSING CONCERN. gtgt Ragavendra Baliga, MD The older betablockers are doubleedged swords. They save lives, but you want to avoid complications down the road. gtgtNarrator DOCTOR RAGAVENDRA BALIGA pronounced rahguhVENDruh BALihguh IS A CARDIOLOGIST AT THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER. HE SAYS OLDER CLASSES OF BETA BLOCKERS INCREASE A PATIENT'S RISK OF DIABETES MORE THAN 25PERCENT.
AND IN A NATIONAL EDITORIAL HE URGED DOCTORS TO SWITCH TO NEWER BETA BLOCKERS TO TREAT HEART FAILURE. gtgt Ragavendra Baliga, MD Diabetes down the road probably will cause more heart attacks, more strokes, more peripheral vascular disease, more renal disease, and a variety of conditions. gtgtNarrator THE NEWER VERSIONS OF BETA BLOCKERS WHICH APPEAR TO CARRY LESS RISK OF DIABETES, BUT THAT'S SOMETHING MARK AND HIS DOCTOR ARE KEEPING A CLOSE EYE ON. MARK HAD A BROTHER WITH DIABETES AND KNOWS ALL TOO WELL WHAT IT CAN DO. gtgtMark Bero He had complications with his diabetes, and went into a diabetic coma.
Clonidine. Clonidine is a highyield topic. We give it a four out of five on our yield scale. It's also called Catapres, which is the common brandname. It is a Alpha 2 agonist. So, let's remind ourselves what the normal physiology is first. So, these vessicles, filled with neurotransmitter, fuse with the membrane and spill out their contents. The Alpha 2 receptors act as a feedback mechanism that decrease the release of neurotransmitter from the presynaptic nerve. Thus, those postsynaptic receptors that you can see down there, are stimulated less and the net effect is a decrease in the sympathetic tone. Now, on to the mechanism.
Of action and the Clinical Uses. Clonidine, as we said, is an Alpha 2 agonist mostly in the Central Nervous System, specifically the vasomotor centers in the medulla oblongata. So really the highyield point here is that this is decreasing the sympathetic tone in the vasomotor centers. Okay, that's five out of five you've got to understand that. The next bullet there just explains in a little bit more detail it's kind of what we already said about how Alpha 2 decreases the release of Norepinephrine through a negative feedback.
System, decreasing the sympathetic tone and the effect is decreased vasocontriction and a decrease in the peripheral vascular resistance and thus a decrease in the blood pressure. Clonidine really does work pretty well. Clinical uses Obviously, we use this to decrease blood pressure for people who are hypertensive, but also, we can use it in the treatment of drug withdrawal. So, physiologically, it is very stressful to withdraw yourself from a drug. Your body has a lot of sympathetic tone as it's trying to adjust to life without that drug that it needed, it's uncomfortable, you feel fidgety, you feel agitated. Clonidine.
Can decrease those effects by the same mechanism we just talked about a decrease in the sympathetic tone. So, while it won't completely alleviate the symptoms, it does make it a little bit more comfortable to go through. For the side effects of Clonidine, the highestyield bullet here 5 out of 5 Rebound Hypertension if you stop it quickly. So, basically, you need to taper this medicine, especially if someone has been on it for a long time and has acclimatized to it, you can't just yank it away from them. Remember, these are people who are already.
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